Due to his performances in the league and the Libertadores, Enzo Fernandéz earned a transfer to an European club. In the case of the Libertadores 22, Enzo was the midfielder with the highest average rating in the competition.
| Player | Rating | Defense | Minutes Played | Team |
| Enzo Fernández | 8.54 | Back 4 | 662 | River Plate |
| Everton Ribeiro | 8.36 | Back 4 | 712 | Flamengo |
| Óscar Romero | 8.31 | Back 4 | 732 | Boca Juniors |
| Allan | 8.19 | Back 4 | 637 | Atlético Mineiro |
| Felipe Gutiérrez | 8.19 | Back 4 | 439 | Univ Católica |
| Giorgian De Arrascaeta | 8.18 | Back 4 | 757 | Flamengo |
| Enzo Pérez | 8.13 | Back 4 | 612 | River Plate |
| Pablo Ceppelini | 7.99 | Back 4 | 431 | Peñarol |
| Nicolás De La Cruz | 7.97 | Back 4 | 574 | River Plate |
| Gabriel Veron | 7.94 | Back 4 | 271 | Palmeiras |
| Kevin Velasco | 7.90 | Back 4 | 449 | AD Cali |
| Fernando Zuqui | 7.88 | Back 5 | 511 | Estudiantes |
| Sebastián Rodríguez | 7.82 | Back 4 | 679 | CS Emelec |
| Claudio Aquino | 7.81 | Back 4 | 602 | Cerro Porteño |
| Rodrigo Aliendro | 7.79 | Back 5 | 359 | Colón |
| Maurice Cova | 7.78 | Back 4 | 450 | Deportivo Táchira |
| Pol Fernández | 7.75 | Back 4 | 660 | Boca Juniors |
| Tomás Cuello | 7.74 | Back 4 | 659 | Atlético Paranaense |
| Thiago Maia | 7.72 | Back 4 | 533 | Flamengo |
| Lorenzo Faravelli | 7.67 | Back 5 | 311 | Independiente del Valle |
| Lucas Janson | 7.63 | Back 4 | 1020 | Vélez Sarsfield |
| Matías Esquivel | 7.62 | Back 4 | 288 | Talleres |
| Dudu | 7.60 | Back 4 | 653 | Palmeiras |
| Anderson Plata | 7.52 | Back 4 | 511 | Tolima |
| Joel Soñora | 7.50 | Back 4 | 332 | Vélez Sarsfield |
| João Gomes | 7.47 | Back 4 | 655 | Flamengo |
| Joao Joshimar Rojas | 7.44 | Back 4 | 439 | CS Emelec |
| Edson Castillo | 7.43 | Back 4 | 352 | Caracas |
| Renato Augusto | 7.43 | Back 4 | 345 | Corinthians |
| Yonathan Rodríguez | 7.43 | Back 4 | 486 | Nacional |
| Gustavo Scarpa | 7.39 | Back 4 | 585 | Palmeiras |
| Federico Lértora | 7.38 | Back 4 | 270 | Colón |
| Fernando Saucedo | 7.28 | Back 4 | 481 | The Strongest |
| Yerson Chacón | 7.25 | Back 4 | 342 | Deportivo Táchira |
| Eduardo Salvio | 7.24 | Back 4 | 415 | Boca Juniors |
| Gabriel Costa | 7.24 | Back 4 | 509 | Colo-Colo |
| Christian Bernardi | 7.24 | Back 5 | 448 | Colón |
| Federico Lértora | 7.24 | Back 5 | 449 | Colón |
| Fernando Cardozo | 7.19 | Back 4 | 332 | Club Olimpia |
| Wesley | 7.19 | Back 4 | 342 | Palmeiras |
| Yoshimar Yotún | 7.19 | Back 4 | 303 | Sporting Cristal |
| Dixon Arroyo | 7.16 | Back 4 | 720 | CS Emelec |
| Lorenzo Melgarejo | 7.15 | Back 4 | 564 | Libertad |
| Cristian Pellerano | 7.14 | Back 5 | 513 | Independiente del Valle |
| Jair | 7.12 | Back 4 | 600 | Atlético Mineiro |
| Ángel Cardozo | 7.11 | Back 4 | 523 | Cerro Porteño |
| David Terans | 7.10 | Back 4 | 636 | Atlético Paranaense |
| Luciano Ursino | 7.09 | Back 4 | 517 | The Strongest |
| Alexis Zapata | 7.08 | Back 4 | 483 | CS Emelec |
| Máximo Perrone | 7.07 | Back 4 | 847 | Vélez Sarsfield |
| Raphael Veiga | 7.07 | Back 4 | 556 | Palmeiras |
| Ezequiel Barco | 7.06 | Back 4 | 379 | River Plate |
| Ignacio Fernández | 7.06 | Back 4 | 661 | Atlético Mineiro |
| Felipe Carballo | 7.05 | Back 4 | 439 | Nacional |
| Fernandinho | 7.05 | Back 4 | 441 | Atlético Paranaense |
| Leonardo Gil | 7.05 | Back 4 | 459 | Colo-Colo |
| Zé Rafael | 7.05 | Back 4 | 798 | Palmeiras |
| Eduard Atuesta | 7.04 | Back 4 | 320 | Palmeiras |
| Jorge Rodríguez | 7.03 | Back 4 | 270 | Estudiantes |
| Gustavo Cristaldo | 7.00 | Back 4 | 325 | Always Ready |
| Jeison Lucumí | 7.00 | Back 4 | 502 | Tolima |
Conditions for the presented data:
– Minimum minutes played in the competition: 270 minutes (equivalent to 3 full games) per type of defense played (Back 4 or Back 5);
– Libertadores Qualifying Round data excluded;
Data from FBref.