As expected, due to the high level presented by the Brazilian and Argentinian teams, this list is mainly represented by teams from these countries. The highest average rating was achieved by Guilherme Arana, FB of Atlético Mineiro.
| Player | Rating | Defense | Minutes Played | Team |
| Guilherme Arana | 7.83 | Back 4 | 703 | Atlético Mineiro |
| Camilo Cándido | 7.51 | Back 4 | 382 | Nacional |
| Abner | 7.49 | Back 4 | 945 | Atlético Paranaense |
| Eduardo Fereira | 7.45 | Back 4 | 450 | Caracas |
| Emmanuel Mas | 7.42 | Back 5 | 540 | Estudiantes |
| Mayke | 7.35 | Back 4 | 449 | Palmeiras |
| Jorge | 7.33 | Back 4 | 305 | Palmeiras |
| Fagner | 7.22 | Back 4 | 405 | Corinthians |
| Rodinei | 7.19 | Back 4 | 669 | Flamengo |
| Eric Meza | 7.17 | Back 4 | 270 | Colón |
| Bryan Carabalí | 7.14 | Back 4 | 360 | CS Emelec |
| Lucas Piton | 7.14 | Back 4 | 293 | Corinthians |
| Enzo Díaz | 7.03 | Back 4 | 860 | Talleres |
| Frank Fabra | 7.02 | Back 4 | 660 | Boca Juniors |
Conditions for the presented data:
– Minimum minutes played in the competition: 270 minutes (equivalent to 3 full games) per type of defense played (Back 4 or Back 5);
– Libertadores Qualifying Round data excluded;
Data from FBref.